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9 p, 484.1 KB |
Classification of suicidal thoughts and behaviour in children : results from penalised logistic regression analyses in the Adolescent Brain Cognitive Development study
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Van Velzen, L.S. (University of Melbourne) ;
Toenders, Y.J. (Orygen) ;
Avila-Parcet, Aina (Institut d'Investigació Biomèdica Sant Pau) ;
Dinga, R. (Radboud University) ;
Rabinowitz, J.A. (Johns Hopkins University) ;
Campos, A.I. (The University of Queensland) ;
Jahanshad, N. (University of Southern California) ;
Rentería, M.E. (The University of Queensland) ;
Schmaal, L. (Orygen) ;
Universitat Autònoma de Barcelona
Despite efforts to predict suicide risk in children, the ability to reliably identify who will engage in suicide thoughts or behaviours has remained unsuccessful. Aims We apply a novel machine-learning approach and examine whether children with suicide thoughts or behaviours could be differentiated from children without suicide thoughts or behaviours based on a combination of traditional (sociodemographic, physical health, social-environmental, clinical psychiatric) risk factors, but also more novel risk factors (cognitive, neuroimaging and genetic characteristics). [...]
2022 -  10.1192/bjp.2022.7
The British journal of psychiatry, Vol. 220 Núm. 4 (february 2022) , p. 210-218
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135 p, 1.9 MB |
Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias : An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry
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Lewczuk, Piotr (University Hospital of Białystok) ;
Riederer, Peter (University Hospital Würzburg) ;
O'Bryant, Sid E. (University of North Texas Health Science Center) ;
Verbeek, Marcel M. (Radboud Alzheimer center) ;
Dubois, Bruno (Salpêtrièrie Hospital) ;
Visser, Pieter Jelle (Vrije Universiteit Amsterdam) ;
Jellinger, Kurt A. (Institute of Clinical Neurobiology) ;
Engelborghs, Sebastiaan (University Hospital Antwerp (Bèlgica)) ;
Ramirez, Alfredo (University of Cologne) ;
Parnetti, Lucilla (University of Perugia) ;
Jack Jr, Clifford R. (Mayo Clinic) ;
Teunissen, Charlotte E. (VU University Medical Center Amsterdam) ;
Hampel, Harald (heimer (IM2A). Hôpital Pitié-Salpêtrière) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Jessen, Frank (German Center for Neurodegenerative Disorders (DZNE)) ;
Glodzik, Lidia (NYU Langone Medical Center) ;
de Leon, Mony J. (NYU Langone Medical Center) ;
Fagan, Anne M. (Washington University School of Medicine) ;
Molinuevo, José Luis (Hospital Clínic i Provincial de Barcelona) ;
Jansen, Willemijn J. (Maastricht University) ;
Winblad, Bengt (Karolinska Institutet (Estocolm, Suècia)) ;
Shaw, Leslie M. (University of Pennsylvania) ;
Andreasson, Ulf (The Sahlgrenska Academy at the University of Gothenburg) ;
Otto, Markus (University of Ulm) ;
Mollenhauer, Brit (Kassel and University Medical Center Göttingen) ;
Wiltfang, Jens (University of Aveiro) ;
Turner, Martin R. (University of Oxford) ;
Zerr, Inga (German Center for Neurodegenerative Diseases) ;
Handels, Ron (Karolinska Institutet (Estocolm, Suècia)) ;
Thompson, Alexander G. (University of Oxford) ;
Johansson, Gunilla (Karolinska Institutet (Estocolm, Suècia)) ;
Ermann, Natalia (Universitätsklinikum Erlangen. and Friedrich-Alexander Universität Erlangen-Nürnberg) ;
Trojanowski, John Q. (University of Pennsylvania) ;
Karaca, Ilker (University of Bonn) ;
Wagner, Holger (University of Bonn) ;
Oeckl, Patrick (University of Ulm) ;
van Waalwijk van Doorn, Linda (Radboud Alzheimer center) ;
Bjerke, Maria (University of Antwerp) ;
Kapogiannis, Dimitrios (National Institute on Aging/National Institutes of Health (NIA/NIH)) ;
Kuiperij, H.Bea (Radboud Alzheimer center) ;
Farotti, Lucia (University of Perugia) ;
Li, Yi (NYU Langone Medical Center) ;
Gordon, Brian A. (Washington University School of Medicine) ;
Epelbaum, Stéphane (Institut de la Mémoire et de la Maladie d'Alzheimer (IM2A)) ;
Vos, Stephanie J.B. (Maastricht University) ;
Klijn, Catharina J.M. (Radboud Alzheimer Center) ;
Van Nostrand, William E. (Stony Brook University) ;
Minguillon, Carolina (Fundació Pasqual Maragall) ;
Schmitz, Matthias (University Medical School) ;
Gallo, Carla (Universidad Peruana Cayetano Heredia) ;
Lopez Mato, Andrea (Maimonides University) ;
Thibaut, Florence (University Hospital Cochin-Site Tarnier 89 rue d'Assas) ;
Lista, Simone (heimer (IM2A). Hôpital Pitié-Salpêtrière) ;
Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit)) ;
Blennow, Kaj (Sahlgrenska University Hospital (Suècia)) ;
Kornhuber, Johannes (Universitätsklinikum Erlangen) ;
Universitat Autònoma de Barcelona
In the 12 years since the publication of the first Consensus Paper of the WFSBP on biomarkers of neurodegenerative dementias, enormous advancement has taken place in the field, and the Task Force takes now the opportunity to extend and update the original paper. [...]
2018 - 10.1080/15622975.2017.1375556
World Journal of Biological Psychiatry, Vol. 19 Núm. 4 (19 2018) , p. 244-328
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24 p, 305.8 KB |
Diagnostic classification of irritability and oppositionality in youth : a global field study comparing ICD-11 with ICD-10 and DSM-5
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Evans, Spencer C. (Harvard University) ;
Roberts, Michael C. (University of Kansas) ;
Keeley, Jared W. (Virginia Commonwealth University) ;
Rebello, Tahilia J. (Columbia University) ;
de la Peña, Francisco (Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz (Mèxic)) ;
Lochman, John E. (University of Alabama) ;
Burke, Jeffrey D. (University of Connecticut) ;
Fite, Paula J. (University of Kansas) ;
Ezpeleta, Lourdes (Universitat Autònoma de Barcelona) ;
Matthys, Walter (Utrecht University) ;
Youngstrom, Eric A. (University of North Carolina) ;
Matsumoto, Chihiro (Japanese Society of Psychiatry and Neurology) ;
Andrews, Howard F. (Columbia University Medical Center) ;
Medina-Mora, María Elena (Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz (Mèxic)) ;
Ayuso-Mateos, José L. (Universidad Autónoma de Madrid) ;
Khoury, Brigitte (American University of Beirut Medical Center) ;
Kulygina, Mayya (Alekseev Mental Health Clinic (Rússia)) ;
Robles, Rebeca (Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz (Mèxic)) ;
Sharan, Pratap (All India Institute of Medical Sciences (Nova Delhi, Índia)) ;
Zhao, Min (Shanghai Jiao Tong University School of Medicine) ;
Reed, Geoffrey M. (World Health Organization (Suïssa))
Background. Severe irritability has become an important topic in child and adolescent mental health. Based on the available evidence and on public health considerations, WHO classified chronic irritability within oppositional defiant disorder (ODD) in ICD-11, a solution markedly different from DSM-5's (i. [...]
2021 - 10.1111/jcpp.13244
Journal of child psychology and psychiatry and allied disciplines, Vol. 62 Núm. 3 (2021) , p. 303-312
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9 p, 1.1 MB |
Plasma phosphorylated tau 181 predicts amyloid status and conversion to dementia stage dependent on renal function
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Lehmann, Sylvain (IRMB CHU de Montpellier) ;
Schraen-Maschke, Susanna (CHU Lille) ;
Vidal, Jean-Sébastien (APHP) ;
Delaby, Constance (Institut d'Investigació Biomèdica Sant Pau) ;
Blanc, Frédéric (University Hospital of Strasbourg) ;
Paquet, Claire (Centre de Neurologie Cognitive) ;
Allinquant, Bernadette (Inserm) ;
Bombois, Stéphanie (GH Pitié-Salpêtrière) ;
Gabelle, Audrey (Inserm INM) ;
Hanon, Olivier (APHP) ;
Universitat Autònoma de Barcelona
Plasma P-tau181 is an increasingly established diagnostic marker for Alzheimer's disease (AD). Further validation in prospective cohorts is still needed, as well as the study of confounding factors that could influence its blood level. [...]
2023 - 10.1136/jnnp-2022-330540
Journal of Neurology, Neurosurgery, and Psychiatry, Vol. 94 (april 2023) , p. 411-419
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9 p, 608.1 KB |
Characterisation of the safety profile of evobrutinib in over 1000 patients from phase II clinical trials in multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus : an integrated safety analysis
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Montalban, Xavier (Hospital Universitari Vall d'Hebron) ;
Wallace, Daniel (University of California) ;
Genovese, Mark C. (Stanford University) ;
Tomic, Davorka Lucia (Ares Trading SA) ;
Parsons-Rich, Dana (EMD Serono Research & Development Institute) ;
Le Bolay, Claire (Merck Healthcare KGaA) ;
Kao, Amy H. (EMD Serono Research & Development Institute) ;
Guehring, Hans (Merck Healthcare KGaA) ;
Universitat Autònoma de Barcelona
Objective Analyse the integrated safety profile of evobrutinib, a Bruton's tyrosine kinase inhibitor (BTKi), using pooled data from multiple sclerosis (MS), rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) trials. [...]
2022 - 10.1136/jnnp-2022-328799
Journal of Neurology, Neurosurgery, and Psychiatry, Vol. 94 Núm. 1 (2022) , p. 1-9
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11 p, 642.9 KB |
Multidimensional predictors of negative symptoms in antipsychotic-naive first-episode psychosis
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Toll, Alba (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Blanco Hinojo, Laura (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Bergé Baquero, Daniel (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Duran-Jordà, Xavier (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Canosa, Irene (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Legido, Teresa (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Mármol, Federico (Universitat de Barcelona. Departament de Fonaments Clínics) ;
Pérez Solà, Víctor (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Fernández Egea, Emilio (University of Cambridge. Department of Psychiatry and Behavioral and Clinical Neuroscience Institute) ;
Mané, Anna (Institut Hospital del Mar d'Investigacions Mèdiques)
Despite a large body of schizophrenia research, we still have no reliable predictors to guide treatment from illness onset. The present study aimed to identify baseline clinical or neurobiological factors - including peripheral brain-derived neurotrophic factor (BDNF) levels and amygdala or hippocampal relative volumes - that could predict negative symptomatology and persistent negative symptoms in first-episode psychosis after 1 year of follow-up. [...]
2022 - 10.1503/jpn.210138
Journal of Psychiatry & Neuroscience : JPN, Vol. 47 (january 2022) , p. E21-E31
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9 p, 453.5 KB |
Monoamine oxidase A (MAOA) interaction with parenting practices on Callous- Unemotional Traits in Preschoolers
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Pueyo, Natalia (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Navarro, J. B.. (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Fatjó-Vilas, Mar (Universitat de Barcelona. Departament de Biologia Evolutiva, Ecologia i Ciències Ambientals) ;
Osa, Nuria de la (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Penelo Werner, Eva (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Fañanás, L. (Universitat de Barcelona. Departament de Biologia Evolutiva, Ecologia i Ciències Ambientals) ;
Ezpeleta, Lourdes (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut)
Background and Objectives: From a gene-by-environment perspective, parenting in interaction with the polymorphism in the Monoamine oxidase A (MAOA) gene (MAOA-uVNTR) might also be associated with increased callous-unemotional traits (CU) in preschoolers. [...]
2021 - 10.1016/j.ejpsy.2021.02.003
European Journal of Psychiatry, Vol. 35 Núm 4(2021) pp. 225-233
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11 p, 3.9 MB |
Muscle MRI in patients with dysferlinopathy : pattern recognition and implications for clinical trials
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Diaz-Manera, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Fernandez-Torron, Roberto (MRC Centre for Neuromuscular Diseases) ;
LLauger, Jaume (Institut d'Investigació Biomèdica Sant Pau) ;
James, Meredith K. (MRC Centre for Neuromuscular Diseases) ;
Mayhew, Anna (MRC Centre for Neuromuscular Diseases) ;
Smith, Fiona E. (Newcastle University) ;
Moore, Ursula R. (MRC Centre for Neuromuscular Diseases) ;
Blamire, Andrew (Newcastle University) ;
Carlier, Pierre G. (Pitié-Salpêtrière University Hospital) ;
Rufibach, Laura (The Jain Foundation) ;
Mittal, Plavi (The Jain Foundation) ;
Eagle, Michelle (MRC Centre for Neuromuscular Diseases) ;
Jacobs, Marni (George Washington University) ;
Hodgson, Tim (Newcastle University) ;
Wallace, Dorothy (Newcastle University) ;
Ward, Louise (Newcastle University) ;
Smith, Mark (Nationwide Children's Hospital) ;
Stramare, Roberto (University of Padova) ;
Rampado, Alessandro (University of Padova) ;
Sato, Noriko (National Center Hospital, National Center of Neurology and Psychiatry) ;
Tamaru, Takeshi (National Center Hospital, National Center of Neurology and Psychiatry) ;
Harwick, Bruce (CMC Mercy Charlotte, Carolinas Healthcare System Neurosciences Institute) ;
Rico Gala, Susana (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ;
Turk, Suna (Pitié-Salpêtrière University Hospital) ;
Coppenrath, Eva M. (Ludwig-Maximilians-University) ;
Foster, Glenn (Washington University) ;
Bendahan, David (Aix-Marseille Université) ;
Le Fur, Yann (Aix-Marseille Université) ;
Fricke, Stanley T. (Children's National Health System) ;
Otero, Hansel (Children's National Health System) ;
Foster, Sheryl L. (University of Sydney) ;
Peduto, Anthony (University of Sydney) ;
Sawyer, Anne Marie (Stanford University School of Medicine) ;
Hilsden, Heather (MRC Centre for Neuromuscular Diseases) ;
Lochmuller, Hanns (MRC Centre for Neuromuscular Diseases) ;
Grieben, Ulrike (A Joint Co-operation of the Charité Medical Faculty and the Max Delbrück Center for Molecular Medicine) ;
Spuler, Simone (A Joint Co-operation of the Charité Medical Faculty and the Max Delbrück Center for Molecular Medicine) ;
Tesi Rocha, Carolina (Stanford University School of Medicine) ;
Day, John W. (Stanford University School of Medicine) ;
Jones, Kristi J. (Children's Hospital at Westmead, University of Sydney) ;
Bharucha-Goebel, Diana (National Institutes of Health (Bethesda, Estats Units d'Amèrica)) ;
Salort-Campana, Emmanuelle (La Timone Hospital, Aix-Marseille Université) ;
Harms, Matthew (Washington University School of Medicine) ;
Pestronk, Alan (Washington University School of Medicine) ;
Krause, Sabine (Ludwig-Maximilians-University of Munich) ;
Schreiber-Katz, Olivia (Ludwig-Maximilians-University of Munich) ;
Walter, Maggie C. (Ludwig-Maximilians-University of Munich) ;
Paradas, Carmen (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Hogrel, J.Y (AP-HP, G.H. Pitié-Salpêtrière) ;
Stojkovic, Tanya (AP-HP, G.H. Pitié-Salpêtrière) ;
Takeda, Shin'ichi (National Center Hospital, National Center of Neurology and Psychiatry) ;
Mori-Yoshimura, Madoka (National Center Hospital, National Center of Neurology and Psychiatry) ;
Bravver, Elena (Carolinas Healthcare System) ;
Sparks, Susan (Carolinas Healthcare System) ;
Bello, Luca (University of Padova) ;
Semplicini, Claudio (University of Padova) ;
Pegoraro, Elena (University of Padova) ;
Mendell, Jerry R. (Nationwide Children's Hospital) ;
Bushby, Kate (MRC Centre for Neuromuscular Diseases) ;
Straub, Volker (MRC Centre for Neuromuscular Diseases) ;
Universitat Autònoma de Barcelona
Dysferlinopathies are a group of muscle disorders caused by mutations in the DYSF gene. Previous muscle imaging studies describe a selective pattern of muscle involvement in smaller patient cohorts, but a large imaging study across the entire spectrum of the dysferlinopathies had not been performed and previous imaging findings were not correlated with functional tests. [...]
2018 - 10.1136/jnnp-2017-317488
Journal of Neurology, Neurosurgery, and Psychiatry, Vol. 89 (may 2018) , p. 1071-1081
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8 p, 395.8 KB |
Neurodevelopmental risk copy number variants in adults with intellectual disabilities and comorbid psychiatric disorders
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Thygesen, Johan H. (University College London) ;
Wolfe, Kate (University College London) ;
McQuillin, Andrew (University College London) ;
Viñas-Jornet, Marina (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Baena Díez, Neus (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Brison, Nathalie (University Hospitals Leuven (Bèlgica)) ;
D'Haenens, Greet (Bierbeek. St Camillus Psychiatric Hospital) ;
Esteba-Castillo, Susanna (Institut Assistència Sanitària (IAS)) ;
Gabau, Elisabeth (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Ribas-Vidal, Núria (Institut Assistència Sanitària (IAS)) ;
Ruiz, Anna (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Vermeesch, Joris (University Hospitals Leuven (Bèlgica)) ;
Weyts, Eddy (Bierbeek. St Camillus Psychiatric Hospital) ;
Novell, Ramon (Institut Assistència Sanitària (IAS)) ;
Buggenhout, Griet Van (Leuven. University Hospitals Leuven. Department of Human Genetics, Centre for Human Genetics) ;
Strydom, André (University College London) ;
Bass, Nicholas (University College London) ;
Guitart, Míriam (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Vogels, Annick (University Hospitals Leuven (Bèlgica)) ;
Universitat Autònoma de Barcelona
Copy number variants (CNVs) are established risk factors for neurodevelopmental disorders. To date the study of CNVs in psychiatric illness has focused on single disorder populations. The role of CNVs in individuals with intellectual disabilities and psychiatric comorbidities are less well characterised. [...]
2018 - 10.1192/bjp.2017.65
The British journal of psychiatry, Vol. 212 (may 2018) , p. 287-294
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